About the Course
Brachytherapy Clinical Observership Training Program
Program Lead: Prof. Merdan Fayda, MDVenue: Liv Hospital Ulus, Istanbul, TürkiyeTraining Context: Liv Hospital Ulus is a Brachy Academy training center by Elekta and hosts one of the highest-volume brachytherapy clinical practices in Istanbul, Türkiye.Program Format: Observational clinical training only — no hands-on practiceDuration Options: 1 week or 2 weeks
Program Overview
This Brachytherapy Clinical Observership Training Program is designed for radiation oncologists, medical physicists, residents, fellows, radiation therapists, dosimetrists, oncology nurses, and other oncology professionals seeking structured exposure to contemporary brachytherapy practice in a high-volume clinical environment.
The program is conducted at Liv Hospital Ulus, Istanbul, Türkiye, a Brachy Academy training center by Elekta, under the leadership of Prof. Merdan Fayda, MD. The center offers participants the opportunity to observe modern brachytherapy workflows within one of the highest-volume brachytherapy clinical practices in Istanbul, Türkiye.
Participants may choose between two duration options:
1-week observership
2-week observership
Both options are strictly observational. The program does not include hands-on practice, independent clinical activity, direct patient care, applicator insertion, contouring responsibility, treatment planning execution, equipment operation, or treatment delivery.
The observership follows the clinical brachytherapy pathway from patient selection and multidisciplinary decision-making through applicator selection, imaging, treatment planning review, quality assurance observation, treatment delivery workflow, and follow-up discussion.
Educational Objectives
By the end of the observership, participants should be able to:
Understand indications and patient selection criteria for contemporary brachytherapy.
Observe the workflow of high-dose-rate brachytherapy in a high-volume center.
Recognize key steps in gynecologic, prostate, breast, skin, and other site-specific brachytherapy cases depending on the clinical schedule.
Understand imaging-based brachytherapy planning principles.
Observe multidisciplinary coordination among radiation oncologists, physicists, dosimetrists, nurses, anesthesiology, and radiation therapists.
Appreciate safety, quality assurance, and radiation protection procedures.
Understand how clinical decision-making is adapted to real-world patient anatomy, disease stage, prior treatments, and institutional workflow.
Describe the complete clinical workflow of modern HDR brachytherapy.
Understand site-specific indications and contraindications for brachytherapy.
Observe patient evaluation, applicator selection, imaging, planning, QA, delivery, and follow-up.
Understand principles of image-guided adaptive brachytherapy.
Compare intracavitary, interstitial, surface, and hybrid brachytherapy approaches.
Recognize common clinical, anatomical, and technical challenges.
Understand medical physics quality assurance and radiation safety processes.
Review practical implementation considerations for establishing or expanding brachytherapy services.
Discuss clinical outcomes, toxicity, patient experience, and follow-up protocols.
Target Participants
This observership is suitable for:
Radiation oncologists
Radiation oncology residents or fellows
Medical physicists
Brachytherapy fellows
Radiation therapists
Dosimetrists
Oncology nurses with brachytherapy interest
Clinical program leaders developing brachytherapy services
International clinicians seeking exposure to Elekta-based brachytherapy workflows
Program Structure
The final schedule is adapted according to clinical case availability, institutional workflow, and patient confidentiality requirements. The following structure outlines the typical observership content.
Core Observership Modules
Module 1 — Orientation, Safety, and Clinical Workflow Introduction
Key topics and activities:
Welcome and introduction by Prof. Merdan Fayda, MD
Orientation to Liv Hospital Ulus brachytherapy services
Overview of Brachy Academy training center environment
Review of observership rules, patient confidentiality, and professional conduct
Infection control and radiation safety orientation
Introduction to Elekta brachytherapy platform and departmental workflow
Overview of the complete brachytherapy pathway:
Consultation
Patient selection
Simulation
Applicator selection
Imaging
Contouring review
Treatment planning
Medical physics QA
Treatment delivery
Post-treatment care
Follow-up
Module 2 — Patient Selection and Clinical Decision-Making
Key topics and activities:
Observation of patient consultation or chart review
Review of indications and contraindications for brachytherapy
Discussion of clinical decision-making in common disease sites:
Cervical cancer
Endometrial and vaginal vault cases
Prostate cancer
Breast cancer
Skin and surface lesions
Head and neck cases
Re-irradiation scenarios
Palliative indications
Review of staging, prior treatment history, anatomy, performance status, and treatment goals
Discussion of multidisciplinary coordination and referral pathways
Case-based discussion with Prof. Fayda or the clinical team
Module 3 — Gynecologic Brachytherapy Observation
Key topics and activities:
Observation of gynecologic brachytherapy case preparation
Review of patient evaluation and staging
Discussion of indications for cervical, endometrial, vaginal, and recurrent gynecologic malignancies
Review of anesthesia considerations and patient comfort measures
Observation of applicator selection workflow from an observational standpoint only
Discussion of intracavitary, interstitial, and hybrid techniques
Review of challenging anatomy and residual disease scenarios
Observation of imaging workflow where available
CT/MRI-based anatomy review
Discussion of target volumes and organs at risk
Review of image-guided adaptive brachytherapy principles
Module 4 — Imaging, Contouring, and Treatment Planning Review
Key topics and activities:
Observation of CT/MRI-based planning workflow
Imaging review for applicator position and anatomy
Observation of contouring discussion
Review of target volume concepts
Organs-at-risk evaluation
Discussion of dose prescription and fractionation
Review of dwell positions, dwell times, and dose optimization principles
Plan evaluation and approval workflow
Discussion of common planning challenges and troubleshooting in clinical practice
Review of selected anonymized cases, if available
Module 5 — Medical Physics, Quality Assurance, and Radiation Safety
Key topics and activities:
Observation of medical physics planning workflow
Overview of HDR afterloader principles
Medical physics quality assurance observation
Independent checks and treatment plan verification
Radiation protection and source safety overview
Emergency procedure overview
Treatment delivery checklist review
Team communication and treatment time-out process
Documentation workflow
Discussion of safety culture in high-volume brachytherapy practice
Module 6 — Treatment Delivery Workflow Observation
Key topics and activities:
Observation of treatment delivery preparation
Review of patient positioning and transfer workflow
Observation of treatment room workflow
Review of communication between physician, physicist, therapists, nurses, and anesthesia team
Observation of treatment delivery process from outside hands-on activity
Post-treatment documentation review
Discussion of patient recovery, discharge instructions, and follow-up planning
Module 7 — Site-Specific Brachytherapy Observation
Depending on clinical schedule and institutional availability, participants may observe site-specific brachytherapy cases including:
Cervical cancer brachytherapy
Endometrial and vaginal vault brachytherapy
Interstitial gynecologic brachytherapy
Hybrid intracavitary/interstitial techniques
Prostate brachytherapy
Breast brachytherapy
Skin and surface brachytherapy
Head and neck brachytherapy
Re-irradiation cases
Palliative brachytherapy
Key topics and activities:
Review of site-specific patient selection
Applicator choice and technique selection
Imaging and anatomy review
Planning principles by disease site
Dose constraints and organ-at-risk considerations
Toxicity prevention and follow-up
Clinical outcomes discussion
Case review with Prof. Fayda or clinical team
Module 8 — Advanced Techniques and Complex Case Discussion
This module is especially emphasized during the 2-week observership option.
Key topics and activities:
Intracavitary versus interstitial decision-making
Hybrid applicator techniques
Complex gynecologic brachytherapy cases
Bulky residual cervical tumors
Recurrent pelvic disease
Prior radiation and re-irradiation
Challenging anatomy
Organ-at-risk limitations
Adaptive planning concepts
Multidisciplinary planning considerations
Review of complex or anonymized cases, if available
Module 9 — Outcomes, Toxicity, Follow-Up, and Patient Experience
Key topics and activities:
Observation of follow-up consultations when available
Review of acute and late toxicity considerations
Discussion of patient counseling and informed consent
Follow-up scheduling and surveillance
Symptom management after brachytherapy
Functional outcomes and quality-of-life considerations
Documentation of treatment response and complications
Patient-centered workflow in a high-volume department
Module 10 — Brachytherapy Service Development and Implementation
This module is particularly relevant for participants seeking to develop or expand brachytherapy services in their own institutions.
Key topics and activities:
Developing or expanding a brachytherapy service
Patient referral pathways
Team composition
Equipment requirements
Staff training needs
Workflow standardization
Quality assurance culture
Safety protocols
Case volume and program sustainability
Role of structured education through Brachy Academy by Elekta
Practical discussion of implementation barriers in participants’ home institutions
Module 11 — Final Case Review and Program Wrap-Up
Key topics and activities:
Consolidated review of observed workflows
Discussion of key lessons from high-volume brachytherapy practice
Review of common clinical and technical challenges
Individual questions and discussion
Summary teaching session by Prof. Merdan Fayda, MD
Feedback session
Certificate of observership attendance, if applicable
Program closure
Clinical Areas Covered
Depending on patient schedule and institutional availability, the observership may include exposure to:
Gynecologic brachytherapy
Cervical cancer intracavitary/interstitial brachytherapy
Vaginal cuff brachytherapy
Endometrial brachytherapy
Prostate brachytherapy
Breast brachytherapy
Skin and surface brachytherapy
Head and neck brachytherapy
Re-irradiation scenarios
Palliative brachytherapy
Image-guided adaptive brachytherapy
HDR brachytherapy workflow
Elekta-based planning and delivery systems
Medical physics QA
Radiation safety procedures
Multidisciplinary brachytherapy workflow
Observational Scope
Participants may observe:
Patient consultation and chart review
Multidisciplinary case discussion
Applicator selection rationale
Imaging workflow
Contouring review
Treatment planning discussion
Medical physics QA
Treatment delivery workflow
Post-treatment care and follow-up discussion
Departmental workflow organization
Clinical case review sessions
Participants may not:
Perform patient examination
Insert, remove, or manipulate applicators
Create, modify, or approve treatment plans
Perform contouring as part of clinical care
Operate treatment equipment
Approve clinical decisions
Deliver radiation treatment
Access patient information outside approved supervision
Participate in hands-on clinical procedures
Provide direct patient care
Faculty and Supervision
The program is led by:
Prof. Merdan Fayda, MDRadiation OncologyLiv Hospital Ulus, Istanbul, Türkiye
Training and observational activities are conducted under the supervision of Prof. Fayda and the Liv Hospital Ulus brachytherapy team, including radiation oncologists, medical physicists, dosimetrists, nurses, anesthesiology, and radiation therapists as appropriate.
Program Deliverables
Participants may receive:
Structured observership schedule
Clinical workflow orientation
Case-based discussions
Exposure to high-volume brachytherapy practice
Observation of Elekta-based brachytherapy workflows
Attendance certificate, subject to institutional approval
Recommendations for further training or implementation planning
Compliance and Confidentiality
All observers must comply with:
Liv Hospital Ulus institutional policies
Patient confidentiality and data protection rules
Infection control procedures
Radiation safety regulations
Professional conduct standards
Observership limitations and non-hands-on requirements
Important Notes
The program is observational only.
No hands-on applicator placement, treatment planning, contouring, machine operation, or treatment delivery is permitted.
Patient privacy, institutional policies, and clinical schedule determine the exact case exposure.
Program content may be adjusted according to real-time clinical workload.
Case availability may vary during the selected observership period.
All activities are subject to approval by Liv Hospital Ulus and relevant clinical teams.
Key Program Message
This Brachytherapy Clinical Observership Training Program offers a structured opportunity to observe contemporary brachytherapy practice at Liv Hospital Ulus, an Elekta Brachy Academy training center, under the leadership of Prof. Merdan Fayda, MD.
The program emphasizes real-world clinical workflow, multidisciplinary teamwork, image-guided planning concepts, quality-focused treatment delivery, radiation safety, and practical decision-making in one of Istanbul’s highest-volume brachytherapy practices. Participants may select either the 1-week or 2-week observership option according to their educational goals and availability.
Your Instructor
Prof Merdan Fayda, MD - Radiation Oncologist

Prof. Merdan Fayda, MD — Academic CV Summary
Prof. Merdan Fayda, MD is a radiation oncology specialist affiliated with Istinye University and Liv Hospital Ulus, Istanbul, Türkiye. He is recognized for his clinical and academic work in radiation oncology, with particular experience in brachytherapy, gynecologic oncology, breast cancer, head and neck cancers, lung cancer, rectal cancer, and advanced radiotherapy techniques.
He serves at Liv Hospital Ulus, a Brachy Academy training center by Elekta, where he leads high-volume brachytherapy practice and clinical observership training activities.
Researcher Profiles
Web of Science ResearcherID: AAF-7370-2019
ORCID: 0000-0002-2800-5327
Web of Science Profile: Merdan Fayda Web of Science Profile
Current Affiliations
Istinye University
Liv Hospital Ulus
Academic and Publication Metrics
Based on Web of Science data prepared on May 23, 2025, covering publications from May 1999 to May 2025:
H-index: 13
Total publications: 62
Web of Science Core Collection publications: 62
Sum of times cited: 452
Areas of Clinical and Academic Expertise
Prof. Fayda’s academic output reflects broad expertise across radiation oncology and oncology-related disciplines, including:
Brachytherapy
Gynecologic brachytherapy
Image-guided adaptive brachytherapy
Combined intracavitary/interstitial brachytherapy
Breast cancer radiotherapy
Postmastectomy radiotherapy
Prostate cancer radiotherapy
Head and neck cancer radiotherapy
Lung cancer radiotherapy
Rectal cancer chemoradiotherapy
Stereotactic body radiation therapy
CyberKnife radiosurgery
Soft tissue sarcoma management
Pediatric oncology-related radiotherapy studies
Radiation pneumonitis and thoracic radiation toxicity
Treatment planning and dosimetric evaluation
MR-guided radiotherapy
Translational oncology and biomarker research
Selected Brachytherapy-Related Publications
Prof. Fayda has contributed to academic work directly related to brachytherapy and advanced image-guided treatment workflows.
Computed Tomography-Guided Optimization of Needle Insertion for Combined Intracavitary/Interstitial Brachytherapy With Utrecht Applicator in Locally Advanced Cervical Cancer
Authors: Tambas, Makbule; Tavli, Busra; et al.; Fayda, Merdan
Published: July 2021
Journal: Practical Radiation Oncology
DOI: 10.1016/J.PRRO.2021.01.008
Times cited: 11
This publication focuses on CT-guided optimization of needle insertion for combined intracavitary/interstitial brachytherapy using the Utrecht applicator in locally advanced cervical cancer.
Istanbul University Istanbul Medical Faculty’s Experience in Brachytherapy for Gynecologic Tumors
Authors: Aslay, Isik; Kemikler, Gonul; et al.
Published: 2012
Journal: Turk Onkoloji Dergisi
Accession Number: WOS:000439266000011
Times cited: 0
This work reflects clinical experience in brachytherapy for gynecologic tumors.
The Three-Dimensional Endobronchial Brachytherapy After Argon Plasma Coagulation
Authors: Fayda, Merdan; Ilgazli, Ahmet; et al.
Published: 2012
Journal: Turkish Journal of Thoracic and Cardiovascular Surgery
DOI: 10.5606/TGKDC.DERGISI.2012.133
Times cited: 0
This publication addresses three-dimensional endobronchial brachytherapy following argon plasma coagulation.
Selected Publications
Having ypN0 May Not Be Enough to Abandon the Postmastectomy Radiotherapy in HER2-Positive Patients
Author: Fayda, Merdan
Published: August 2023
Journal: Radiotherapy and Oncology
DOI: 10.1016/J.RADONC.2023.109722
Times cited: 0
Clinical Utility of a 1.5 T Magnetic Resonance Imaging-Guided Linear Accelerator During Conventionally Fractionated and Hypofractionated Prostate Cancer Radiotherapy
Authors: Turkkan, Gorkem; Bilici, Nazli; et al.; Fayda, Merdan
Published: August 2022
Journal: Frontiers in Oncology
DOI: 10.3389/FONC.2022.909402
Times cited: 2
Cardiotoxicity After the Lymphoma
Authors: Ozen, Alaattin; Fayda, Merdan
Published: 2022
Journal: Turk Onkoloji Dergisi
DOI: 10.5505/TJO.2022.S1007
Times cited: 0
Dosimetric Comparison of Volumetric-Modulated Arc Therapy and Dynamic Conformal Arc Therapy in Three-Fraction Single-Isocenter Stereotactic Radiosurgery for Multiple Brain Metastases
Authors: Turkkan, Gorkem; Bilici, Nazli; et al.; Fayda, Merdan
Published: 2022
Journal: Turk Onkoloji Dergisi
DOI: 10.5505/TJO.2021.3412
Times cited: 2
Neoadjuvant Volumetric Modulated Arc Therapy in Rectal Cancer and the Correlation of Pathological Response With Diffusion-Weighted MRI and Apoptotic Markers
Authors: Gurdal, Necla; Fayda, Merdan; et al.
Published: August 2018
Journal: Tumori Journal
DOI: 10.5301/TJ.5000702
Times cited: 2
Development of Independent MU/Treatment Time Verification Algorithm for Non-IMRT Treatment Planning: A Clinical Experience
Authors: Tatli, Hamza; Yucel, Derya; et al.; Fayda, Merdan
Published: 2018
Journal: AIP Conference Proceedings
DOI: 10.1063/1.5025987
Times cited: 0
Loss of ARID1A Expression Is Associated With Poor Prognosis in Invasive Micropapillary Carcinomas of the Breast: A Clinicopathologic and Immunohistochemical Study With Long-Term Survival Analysis
Authors: Onder, Semen; Fayda, Merdan; et al.
Published: November 2017
Journal: The Breast Journal
DOI: 10.1111/TBJ.12823
Times cited: 12
Dosimetric Comparison of 3-Dimensional Conformal and Intensity-Modulated Radiotherapy Techniques for Whole Breast Irradiation in the Prone and Supine Positions
Authors: Koksal, C.; Kesen, N. D.; et al.
Published: October 2017
Journal: International Journal of Radiation Research
DOI: 10.18869/ACADPUB.IJRR.15.4.353
Times cited: 4
Do Circulating Long Non-Coding RNAs Predict the Treatment Response in Patients With Head and Neck Cancer Treated With Chemoradiotherapy?
Full title: Do circulating long non-coding RNAs — LincRNA-p21, GAS5, HOTAIR — predict the treatment response in patients with head and neck cancer treated with chemoradiotherapy?
Authors: Fayda, Merdan; Isin, Mustafa; et al.
Published: March 2016
Journal: Tumor Biology
DOI: 10.1007/S13277-015-4189-1
Times cited: 63
GAS5 Oligonucleotides as Therapeutic Agents in Breast Cancer
Authors: Fayda, Merdan; Gezer, Ugur
Published: 2016
Journal: Translational Cancer Research
DOI: 10.21037/TCR.2016.08.42
Times cited: 4
Is Sentinel Lymph Node Biopsy Enough for Axillary Macrometastasis?
Authors: Fayda, Merdan; Tambas, Makbule; Karanlik, Hasan
Published: December 2015
Journal: Turkish Journal of Surgery
DOI: 10.5152/UCD.2015.3076
Times cited: 0
Metaplastic Breast Carcinoma Versus Triple-Negative Breast Cancer: Survival and Response to Treatment
Authors: Aydiner, Adnan; Sen, Fatma; et al.
Published: December 2015
Journal: Medicine
DOI: 10.1097/MD.0000000000002341
Times cited: 51
Intraoperative Ultrasound Reduces the Need for Re-Excision in Breast-Conserving Surgery
Authors: Karanlik, Hasan; Ozgur, Ilker; et al.
Published: November 2015
Journal: World Journal of Surgical Oncology
DOI: 10.1186/S12957-015-0731-2
Times cited: 25
Axillary Versus Sentinel-Lymph-Node Dissection for Micrometastatic Breast Cancer
Authors: Fayda, Merdan; Karanlik, Hasan
Published: 2013
Journal: The Lancet Oncology
DOI: 10.1016/S1470-2045(13)70195-5
Times cited: 2
Challenges Scoring Radiation Pneumonitis in Patients Irradiated for Lung Cancer
Authors: Yirmibesoglu, Eda; Higginson, Daniel S.; et al.; Marks, Lawrence B.
Published: 2012
Journal: Lung Cancer
DOI: 10.1016/J.LUNGCAN.2011.11.025
Times cited: 36
Axillary vs Sentinel Lymph Node Dissection for Invasive Breast Cancer
Authors: Fayda, Merdan; Chen, Ronald
Published: June 2011
Journal: JAMA
DOI: 10.1001/JAMA.2011.753
Times cited: 3
The Comparison of Weekly and Three-Weekly Cisplatin Chemotherapy Concurrent With Radiotherapy in Patients With Previously Untreated Inoperable Non-Metastatic Squamous Cell Carcinoma of the Head and Neck
Authors: Uygun, Kazim; Bilici, Ahmet; et al.
Published: July 2009
Journal: Cancer Chemotherapy and Pharmacology
DOI: 10.1007/S00280-008-0911-7
Times cited: 39
The Role of Surgery and Radiotherapy in Treatment of Soft Tissue Sarcomas of the Head and Neck Region: Review of 30 Cases
Authors: Fayda, Merdan; Aksu, Gorkem; et al.
Published: 2009
Journal: Journal of Cranio-Maxillofacial Surgery
DOI: 10.1016/J.JCMS.2008.07.007
Times cited: 37
Treatment Results and Prognostic Factors in Oral Tongue Cancer: Analysis of 80 Patients
Authors: Aksu, G.; Karadeniz, A.; et al.
Published: 2006
Journal: International Journal of Oral and Maxillofacial Surgery
DOI: 10.1016/J.IJOM.2006.01.006
Times cited: 34
Primary Glioblastoma Multiforme in Younger Patients: A Single-Institution Experience
Authors: Ulutin, Cuneyt; Fayda, Merdan; et al.
Published: 2006
Journal: Tumori Journal
DOI: 10.1177/030089160609200507
Times cited: 21
The Value of Postoperative Radiotherapy in Renal Cell Carcinoma: A Single-Institution Experience
Authors: Ulutin, H. Cuneyt; Aksu, Gorkem; et al.
Published: 2006
Journal: Tumori Journal
DOI: 10.1177/030089160609200303
Times cited: 19
Peer Review Activity
According to the Web of Science CV prepared on May 23, 2025, Prof. Fayda has verified peer review activity including:
4 verified reviews
2 manuscripts reviewed
Examples include peer review activity for:
Science Progress
Manuscript: Value of postmastectomy radiotherapy on overall survival in stage II–III ypN0 patients following neoadjuvant therapy: a SEER-based population study
Review period: March 2025 to April 2025
International Journal of Cancer
Manuscript: Clinicopathological and prognostic features of nasopharyngeal carcinoma in children and adolescents: A retrospective study of 196 cases in South China
Review period: March 2020 to July 2020
Website-Ready Short Biography
Prof. Merdan Fayda, MD is a radiation oncology specialist affiliated with Istinye University and Liv Hospital Ulus, Istanbul, Türkiye. He has extensive clinical and academic experience in modern radiation oncology, with a particular focus on brachytherapy, gynecologic oncology, breast cancer, head and neck cancers, lung cancer, rectal cancer, and advanced radiotherapy techniques.
He practices at Liv Hospital Ulus, an Elekta Brachy Academy training center, where he leads high-volume brachytherapy activities and clinical observership training. His academic record includes 62 Web of Science Core Collection publications, an H-index of 13, and 452 citations according to Web of Science data prepared in May 2025.
Prof. Fayda’s research includes work on combined intracavitary/interstitial brachytherapy, image-guided radiotherapy, breast cancer radiotherapy, head and neck chemoradiotherapy, thoracic radiation toxicity, stereotactic radiotherapy, and translational oncology. He has also contributed to peer review for international scientific journals.
Website-Ready Condensed Version
Prof. Merdan Fayda, MD is a radiation oncology specialist affiliated with Istinye University and Liv Hospital Ulus, Istanbul, Türkiye. He is actively involved in high-volume brachytherapy practice at Liv Hospital Ulus, an Elekta Brachy Academy training center.
According to Web of Science data prepared in May 2025, Prof. Fayda has 62 Web of Science Core Collection publications, an H-index of 13, and 452 citations. His academic and clinical work focuses on brachytherapy, gynecologic oncology, breast cancer radiotherapy, head and neck cancers, lung cancer, rectal cancer, image-guided radiotherapy, and advanced treatment planning.
His publications include studies on combined intracavitary/interstitial brachytherapy, MR-guided radiotherapy, postmastectomy radiotherapy, chemoradiotherapy, stereotactic radiotherapy, and radiation-related toxicity.

